The overall goal of Martin's academic program is to develop and communicate the scientific knowledge needed to prevent and control foodborne and zoonotic diseases caused by bacteria as well as microbial food spoilage. With his training as a both a veterinarian and food scientist, Martin's programs focus on a comprehensive and interdisciplinary farm-to-table approach to food safety and quality. Martin also serves as co-director of the New York State Integrated Food Safety Center of Excellence.
The specific objective of my research program is to develop a better understanding of the pathogenesis, ecology, evolution, and transmission of bacterial foodborne and zoonotic diseases. The pathogenesis of foodborne and zoonotic diseases can involve complex interactions between a bacterial pathogen, a variety of environments and one or multiple host species. The ability of bacterial cells to survive and compete in a variety of environments plays a key role in the pathogenesis and transmission of many foodborne diseases. In addition, selective pressures not associated with mammalian hosts may contribute significantly to the emergence and evolution of virulence characteristics related to the ability of bacteria to effectively infect mammalian hosts. Foodborne zoonotic pathogens provide ideal model systems for studying the ecology of infectious diseases, including adaptation of clonal groups to specific hosts and non-host environments as well as virulence gene expression and maintenance of virulence characteristics under widely varying conditions, including those not directly associated with a host. Current work in my laboratory focuses on two model organisms, including

Listeria monocytogenes, which causes disease in more than 20 animal species as well as a severe, but rare human foodborne disease with about 250 human deaths annually in the US alone; and
Salmonella, which causes disease in many mammals as well as a common foodborne disease in humans (1.0 million cases and 300 deaths annually in the US).
My research on understanding the biology of foodborne and zoonotic pathogens is a truly interdisciplinary endeavor. My research thus involves the application of a variety of disciplines (including microbiology and microbial genetics, population genetics, molecular biology, genomics, evolution and modelling) and collaborators from different disciplines.