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    • BioBone – A Prospective, Blinded, Multicenter Validation Study of the CD8 + Terminal Differentiated Effector Memory Cells (CD8 + TEMRA Cells) As Prognostic Biomarker for Disturbed Fracture Healing – Study Design

    Simon Reinke, Anja Maria Bauer， Stefan Weber,Sven Geißler

    Journal of Orthopaedic Surgery and Research（2025）

    Charité – Universitätsmedizin Berlin

    Cited 0|Views0
    Abstract
    The BioBone consortium aims to validate circulating CD8 + TEMRA cells as a prognostic biomarker for predicting impaired fracture healing outcomes in a prospective, blinded, multicenter clinical study. The primary performance parameters are the pre-operative identification of at least 30
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    Key words
    Long bone fracture,Impaired healing,CD8 + TEMRA,Prognostic biomarker
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