Safety and Efficacy of Low-Intensity Versus Standard Monitoring Following Intravenous Thrombolytic Treatment in Patients with Acute Ischaemic Stroke (optimistmain): an International, Pragmatic, Stepped-Wedge, Cluster-Randomised, Controlled Non-Inferiority Trial.

Craig S Anderson,Debbie Summers, Menglu Ouyang,Yi Sui,Brenda Johnson,Laurent Billot,Alejandra Malavera,Roland Faigle,Paula Muñoz-Venturelli, Diana Day,Xiaoqiu Liu,Qiang Li,Lili Song, Thompson G Robinson,Francisca González, Francisca Urrutia-Goldsack, Michael Iacobelli, Michelle Montalbano, April Pruski,Candice Delcourt, Alice C Durham, Ahtasam Ebraimo, Ha Hong Van Ta, Pratiti Ghosh, Ann Leonhardt-Caprio,Huy Thang Nguyen, Mai Duy Ton,Stephen Jan,Hueiming Liu, Richard I Lindley,Antonio Arauz, Andrés Mercado,Wan Asyraf Wan Zaidi,Pooja Khatri,Xia Wang,Victor C Urrutia, OPTIMISTmain Investigators

Lancet (London, England)（2025）

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