WeChat Mini Program
Old Version Features

FpCBS Affects a Diverse Range of Functions of Fusarium Pseudograminearum Impacting Its Virulence to Wheat.

Jie Zhang, Qiuyuan Chai, Paul H Goodwin, Wenqian Zhu,Mingcong Xia,Runhong Sun,Wen Xu,Chao Wu, Yajing Song, Qianqian Dong,Lirong Yang

Plant, cell & environment(2025)

Cited 0|Views0
Abstract
A cystathionine β-synthase (CBS) gene, FpCBS, of the wheat crown rot pathogen, Fusarium pseudograminearum, was identified. FpCBS was highly expressed during conidiation and the early phases of infection. Compared to the wild-type and FpCBS complemented strains, the FpCBS deletion strain had a similar hyphal morphology and growth rate but reduced conidiation. In culture, the FpCBS deletion strain showed broad-scale changes with a decrease in H2S levels, changes in sulphur-containing amino acids and 1207 differentially expressed proteins. The deletion strain also showed reduced deoxynivalenol (DON) production, cellophane penetration ability, antioxidant capacity, as well as increased hyphal iron levels, sensitivity to H2O2 and lipid peroxidation. During infection, the ΔFpcbs strain showed diminished virulence to wheat with fewer penetration structures, and there was a stronger host defence response with wheat epidermal cells having thickened walls and greater reactive oxygen species accumulation. Transcriptomic analysis of infected leaves showed 1954 differentially expressed genes in the FpCBS deletion strain compared to the wild-type strain. This included genes for sulphur metabolism, antioxidative defence, plant cell wall-degrading enzymes and trichothecene production. FpCBS not only plays a pivotal role in sulphur metabolism and H2S production, but it is also important for a broad range of fungal functions, including iron homoeostasis, mycotoxin production and development (conidiation and penetration structures). These factors may all contribute to varying extents to the significant decrease in virulence of the FpCBS deletion strain. The findings have shown that FpCBS is important for much more than sulphur metabolism and H2S synthesis. However, its role in virulence highlights its potential as a novel target for developing strategies to control wheat crown rot.
More
Translated text
求助PDF
上传PDF
Bibtex
AI Read Science
AI Summary
AI Summary is the key point extracted automatically understanding the full text of the paper, including the background, methods, results, conclusions, icons and other key content, so that you can get the outline of the paper at a glance.
Example
Background
Key content
Introduction
Methods
Results
Related work
Fund
Key content
  • Pretraining has recently greatly promoted the development of natural language processing (NLP)
  • We show that M6 outperforms the baselines in multimodal downstream tasks, and the large M6 with 10 parameters can reach a better performance
  • We propose a method called M6 that is able to process information of multiple modalities and perform both single-modal and cross-modal understanding and generation
  • The model is scaled to large model with 10 billion parameters with sophisticated deployment, and the 10 -parameter M6-large is the largest pretrained model in Chinese
  • Experimental results show that our proposed M6 outperforms the baseline in a number of downstream tasks concerning both single modality and multiple modalities We will continue the pretraining of extremely large models by increasing data to explore the limit of its performance
Upload PDF to Generate Summary
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn
Chat Paper
Summary is being generated by the instructions you defined