Machine Learning Integration of Single-Cell and Bulk Transcriptomics Identifies Fibroblast-Driven Prognostic Markers in Colorectal Cancer

Ning Zhang, Ruiyan Liu, Siya Wu, Chenxi Feng, Boxiang Wang, Qiaoqiao Zheng, Linru Jie,Ruihua Kang, Xiaoli Guo,Xiaoyang Wang,Shaokai Zhang,Jiangong Zhang

Biomolecules & biomedicine（2025）

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Key words

Colorectal cancer,CRC,fibroblasts,prognosis signature,machine learning,therapy

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