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Motor Phenotypes of Amyotrophic Lateral Sclerosis – a Three-Determinant Anatomical Classification Based on the Region of Onset, Propagation of Motor Symptoms, and the Degree of Upper and Lower Motor Neuron Dysfunction

Thomas Meyer,Matthias Boentert,Julian Großkreutz,Patrick Weydt, Sarah Bernsen,Peter Reilich,Robert Steinbach,Annekathrin Rödiger, Joachim Wolf,Ute Weyen,Albert C. Ludolph,Jochen Weishaupt,Susanne Petri,Paul Lingor, René Günther,Wolfgang Löscher,Markus Weber,Christoph Münch, André Maier,Torsten Grehl

Neurological Research and Practice（2025）

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Key words
Amyotrophic lateral sclerosis,Motor phenotypes,Classification,OPM
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