KRAS G12D -Specific Targeting with Engineered Exosomes Reprograms the Immune Microenvironment to Enable Efficacy of Immune Checkpoint Therapy in PDAC Patients.

Valerie S LeBleu,Brandon G Smaglo, Krishnan K Mahadevan,Michelle L Kirtley, Kathleen M McAndrews,Mayela Mendt,Sujuan Yang, Ana S Maldonado,Hikaru Sugimoto, Maria E Salvatierra, Luisa M Solis Soto, Rick Finch, Mihai Gagea, Adam C Fluty, Steve J Ludtke,J Jack Lee, Abhinav K Jain, Gauri Varadhachary,Rachna T Shroff,Anirban Maitra,Elizabeth Shpall,Raghu Kalluri,Shubham Pant

medRxiv the preprint server for health sciences（2025）

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