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Stabilizing Prefusion SARS-CoV-2 Spike by Destabilizing the Postfusion Conformation

Debajyoti Chakraborty,Randhir Singh, Raju S Rajmani,Sahil Kumar,Rajesh P Ringe,Raghavan Varadarajan

Vaccines（2025）

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Key words
stabilization,SARS-CoV-2 Spike,charged amino acids,HR1 and HR2,immunogenicity,COVID-19
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