Targeting CDK4/6 Suppresses Colorectal Cancer by Destabilizing YAP1.

Yalei Wen, Xiao Yang, Shengrong Li, Lei Huang,Jiayi Chen, Lirong Tan, Xiuqing Ma,Yingjie Zhu,Zhengqiu Li,Changliang Shan,Chunze Zhang, Qiushi Zhang, Mingchao Liang,Haoxing Zhang,Tongzheng Liu

MedComm（2025）

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关键词

abemaciclib,colorectal cancer (CRC),cyclin‐dependent kinase 4/6 (CDK4/6),deubiquitinating enzyme 3 (DUB3),Yes‐associated protein 1 (YAP1)

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