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Cross-industry Demonstration of the Validity of the Mixed Matrix Method for the Assessment of Cross-Species Exposure Coverage of Human Circulating Drug Metabolites

Alexander D. James,Christian Lanshoeft, Gregory S. Steeno,Douglas K. Spracklin, Zhiping You,Raman Sharma,Xue-Qing Li,Linda C. Andersson, Isabel Piel, Alison Webb, Janine M. Doyle, Laurent Laboureur, Georges Da Violante, David Rizzo, Yves Martin Siegrist

Drug Metabolism and Disposition(2025)

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