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MaveDB 2024: a Curated Community Database with over Seven Million Variant Effects from Multiplexed Functional Assays

Alan F. Rubin,Jeremy Stone,Aisha Haley Bianchi, Benjamin J. Capodanno, Estelle Y. Da,Mafalda Dias,Daniel Esposito,Jonathan Frazer,Yunfan Fu, Sally B. Grindstaff, Matthew R. Harrington, Iris Li,Abbye E. McEwen,Joseph K. Min, Nick Moore, Olivia G. Moscatelli, Jesslyn Ong, Polina V. Polunina,Joshua E. Rollins,Nathan J. Rollins, Ashley E. Snyder,Amy Tam,Matthew J. Wakefield, Shenyi Sunny Ye,Lea M. Starita,Vanessa L. Bryant,Debora S. Marks,Douglas M. Fowler

Genome Biology（2025）

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Key words

Multiplexed assays of variant effect,MAVEs,Deep mutational scanning,DMS,Variant classification,Functional genomics

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