Access to Axially Chiral Biaryl Benzylamines Via Ancestral Enzyme-Enabled Reductive Amination Desymmetrization

Wen-Qing Zheng, Xin-Xin Zhu, Zheng Zhu, Tairan Yang, Lifen Zheng, Rui Pan,Shenlin Wang,Lixin Zhang,Qi Chen,Jian-He Xu, Yongtao Xie,Gao-Wei Zheng

ACS CATALYSIS（2025）

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关键词

biocatalysis,desymmetrization,reductive amination,ancestral imine reductase,axially chiral biaryl benzylamine

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