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Non-Invasive Determination of the Paternal Inheritance in Pregnancies at Risk for Β-Thalassaemia by Analyzing Cell-Free Fetal DNA Using Targeted Next-Generation Sequencing

Stefania Byrou,Rutger W. W. Brouwer,Marios Tomazou,Stella Tamana,Petros Kountouris,Carsten W. Lederer,Miranda Petrou,Zeliha Ozgur, Xander den Dekker,Zakia Azmani,Soteroula Christou,Christiana Makariou,Marina Kleanthous,Wilfred F. J. van Ijcken,Thessalia Papasavva

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES（2025）

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Key words
non-invasive prenatal testing (NIPT),beta-thalassaemia,cell-free DNA (cfDNA),haplotype analysis,monogenic disorders
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