Metabolic-Immune Suppression Mediated by the SIRT1-CX3CL1 Axis Induces Functional Enhancement of Regulatory T Cells in Colorectal Carcinoma

Ruiyang Zi, Xiang Zhao,Limei Liu, Yijie Wang,Rui Zhang,Zhiheng Bian, Haoran Jiang, Taorui Liu, Yixin Sun, Han Peng, Xuesong Wang, Fanghao Lu,Chao Zhang,Fan Zhang, Qing Qin,Houjie Liang,Jianjun Li, Zhihao Wei,Yan Dong

ADVANCED SCIENCE（2025）

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Key words

Colorectal carcinoma,CX3CL1,Immunosuppression,Regulatory T cell,SIRT1

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