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Phenotype-Led Identification of IL-10 Upregulators in Human CD4+ T-cells and Elucidation of Their Pharmacology As Highly Selective CDK8/CDK19 Inhibitors

Simon Nicolle, Mike Barker,John Barrett, Matthew Campbell,Justyna Wojno-Picon,Stephen J. Atkinson,Helen Aylott, Hripsimee Kessedjian, Yanan He,Cassie Messenger, Emma Roberts, Claus Spitzfaden,Joelle Le,Nico Zinn,Thilo Werner,Birgit Dumpelfeld,Marcus Bantscheff, Don O. Somers, Heather Reid, Kevin Thang,Thomas Gobbetti,Huw D. Lewis

JOURNAL OF MEDICINAL CHEMISTRY（2025）

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