Integrated Single-Cell and Bulk Transcriptome Analysis of R-loop Score-Based Signature with Regard to Immune Microenvironment, Lipid Metabolism and Prognosis in HCC

Long Chen, Houzhi Yang, Xianfu Wei, Jianchao Liu,Xiuxin Han,Chao Zhang,Yongheng Liu,Yan Zhang,Yao Xu, Yiqin Li,Guowen Wang, Jinyan Feng

FRONTIERS IN IMMUNOLOGY（2025）

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Key words

R-loop,single-cell RNA-sequencing,HCC,tumor immune microenvironment,lipid metabolism reprogram,CLTC

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