An Integrative and Translational PKPD Modelling Approach to Explore the Combined Effect of Polymyxin B and Minocycline Against Klebsiella Pneumoniae

Chenyan Zhao,Sanne van den Berg, Zhigang Wang,Anna Olsson,Vincent Aranzana-Climent,Christer Malmberg,Pernilla Lagerbäck,Thomas Tängdén,Anouk E. Muller,Elisabet I. Nielsen,Lena E. Friberg

International Journal of Antimicrobial Agents（2025）

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translational pharmacokinetic-pharmacodynamic modelling,semi-mechanistic pharmacokinetic-pharmacodynamic model,antibiotic combination,polymyxin B,minocycline

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