Functional and Structural Polypharmacology of Indazole-based Privileged Ligands to Tackle the Undruggability of Membrane Transporters

Katja Stefan,Sachin Puri,Muhammad Rafehi, Ganesh Latambale, Maria Neif, Franziska Tägl, Nike Sophia Arlt, Zeinab Nezafat Yazdi,Éva Bakos, Xiang Chen, Bohan Zhang, Wouroud Ismail Al-Khalil, Hauke Busch,Zhe-Sheng Chen,Csilla Özvegy-Laczka,Vigneshwaran Namasivayam,Kapil Juvale,Sven Marcel Stefan

European Journal of Medicinal Chemistry（2025）

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Key words

Solute carrier,monocarboxylate transporter,monoamine transporter,organic anion transporting polypeptide,organic cation transporter,ABC transporter,multitarget binding site

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