Preparation and Pharmacological Characterization of the Enantiomers of the Anticancer Agent R/S-N-3-cyanophenyl-N'-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea: Identification of the R-enantiomer As the Active Eutomer

Michael Schnekenburger,Eric Goffin,Matthieu Schoumacher,Nikolay Tumanov,Ange Mouithys-Mickalad,Pascal de Tullio,Johan Wouters, Philippe Lebrun,Marc Diederich,Bernard Pirotte

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY REPORTS（2025）

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2-Dimethylchromans,Racemate,Enantiomeric separation,Pancreatic B -Cell,Potassium channel opener,Anticancer agent,Glucose metabolism,Sirtuin inhibitor,Leukemia

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