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Functional Screening Reveals Genetic Dependencies and Diverging Cell Cycle Control in Atypical Teratoid Rhabdoid Tumors

Daniel J. Merk,Foteini Tsiami,Sophie Hirsch,Bianca Walter,Lara A. Haeusser, Jens D. Maile,Aaron Stahl,Mohamed A. Jarboui,Anna Lechado-Terradas,Franziska Klose,Sepideh Babaei,Jakob Admard,Nicolas Casadei,Cristiana Roggia,Michael Spohn,Jens Schittenhelm,Stephan Singer,Ulrich Schüller,Federica Piccioni,Nicole S. Persky,Manfred Claassen,Marcos Tatagiba, Philipp J. Kahle,David E. Root,Markus Templin,Ghazaleh Tabatabai

GENOME BIOLOGY（2024）

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关键词
Functional screening,CRISPR-Cas9,Genetic dependencies,Rhabdoid tumors,CDK4/6 inhibitors,AMBRA1,Tumor suppressor
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