Structure-guided Development of Selective Caseinolytic Protease P Agonists As Antistaphylococcal Agents

Tao Zhang, Pengyu Wang, Hailing Zhou,Bingyan Wei, Yanling Zhao, Jiahui Li,Min Zhang,Wenjuan Wu,Lefu Lan,Jianhua Gan,Cai-Guang Yang

CELL REPORTS MEDICINE（2024）

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methicillin-resistant Staphylococcus aureus,MRSA,caseinolytic protease P,ClpP,selective agonist,ZG297,structure guided design,antistaphylococcal agents,antibiotic,murine skin infection model,murine thigh infection model,tyrosine/histidine pairs

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