An Efficient Enzymatic System for Studying Structure-Carcinogenicity Relationships: Metabolism of Pyrrolizidine Alkaloids by Human Liver Microsomes in the Presence of Calf Thymus DNA, Resulting in the Formation of DNA Adducts
JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-TOXICOLOGY AND CARCINOGENESIS(2024)
关键词
Pyrrolizidine alkaloid,DHP-DNA adducts,tumorigenicity biomarker,human liver microsomes,pyrrolic metabolites
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