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Statistical Operating Characteristics of Current Early Phase Dose Finding Designs with Toxicity and Efficacy in Oncology

Hao Sun, Hsin-Yu Lin,Jieqi Tu,Revathi Ananthakrishnan, Eunhee Kim

JOURNAL OF BIOPHARMACEUTICAL STATISTICS(2024)

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关键词
Dose finding,early phase trial design,model-assisted design,optimal biological dose,random toxicity and efficacy probabilities
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