Early Process Development of an LPAR1 Antagonist, GS-2278

Nathaniel Kadunce, Anna M. Wagner,Jeromy Cottell, Kathy Dao,Darryl D. Dixon, Blanka M. Hodur,Dane Holte,Michael A. Ischay, Jihun Kang, Seongtaek Kim, Young Ho Kim, Seung Moh Koo,Willard Lew, Lucas Man, Kashi Reddy Methuku, Henry Morrison, Patrick D. Parker, David A. Siler, Chloe Y. Wong

ORGANIC PROCESS RESEARCH & DEVELOPMENT（2024）

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lysophosphatidic acid,LPAR1,idiopathic pulmonaryfibrosis,hydroxamic acid,Lossen rearrangement,isocyanate,carbamate,Boc-deprotection,amide-coupling,Sakai triazole synthesis

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