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Revealing SARS-CoV-2 Mpro Mutation Cold and Hot Spots: Dynamic Residue Network Analysis Meets Machine Learning

Victor Barozi, Shrestha Chakraborty, Shaylyn Govender, Emily Morgan, Rabelani Ramahala,Stephen C. Graham,Nigel T. Bishop,Ozlem Tastan Bishop

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL(2024)

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Key words
Drug design,Drug resistance,Pathogen evolution,Network analysis,Artificial neural networks,Decision tree,Chymotrypsin-like protease,3CLpro,Nsp5,SARS-CoV,COVID-19,Mpro
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