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Rationale and Design of OPT-RATE AF: A Randomized Clinical Trial of Increased Physiologic Pacing Rates in Heart Failure with Preserved Ejection Fraction

Evan Czulada, Jamal D. Smith,Paul Kolm, Brototo Deb,Sarahfaye F. Dolman,Nebu Alexander, Ryan A. Braun,Rajiv A. Kabadi,William S. Weintraub,David Strouse,Athanasios Thomaides

AMERICAN JOURNAL OF CARDIOLOGY（2025）

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Key words
atrioventricular nodal ablation,cardiac physiologic pacing,heart failure with pre- served ejection fraction,permanent atrial fibrillation
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