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Structure-Guided Conformational Restriction Leading to High-Affinity, Selective, and Cell-Active Tetrahydroisoquinoline-Based Noncovalent Keap1-Nrf2 Inhibitors

Yuting Qin,Cecilie Poulsen,Dilip Narayanan,Camilla B. Chan,Xiangrong Chen, Beatriz Ralsi Montes,Kim T. Tran, Elina Mukminova, Chunyu Lin,Michael Gajhede,Alex N. Bullock,David Olagnier,Anders Bach

JOURNAL OF MEDICINAL CHEMISTRY（2024）

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