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LINE1 and PRC2 Control Nucleolar Organization and Repression of the 8C State in Human ESCs

Juan Zhang, Lamisa Ataei,Kirti Mittal, Liang Wu,Lauren Caldwell, Linh Huynh, Shahil Sarajideen, Kevin Tse,Marie-Michelle Simon, Md. Abdul Mazid,David P. Cook,Daniel Trcka,Tony Kwan,Michael M. Hoffman,Jeffrey L. Wrana,Miguel A. Esteban,Miguel Ramalho-Santos

DEVELOPMENTAL CELL（2025）

Cited 2|Views4
Key words
human embryonic stem cells,8-cell-like cells,LINE1,polycomb repressive complex 2,H3K27me3,nuclear compartmentalization,nucleolus,chromosome 19
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