A Rapidly Progressive Multiple System Atrophy-Cerebellar Variant Model Presenting Marked Glial Reactions with Inflammation and Spreading of Α-Synuclein Oligomers and Phosphorylated Α-Synuclein Aggregates

Hiroo Yamaguchi,Yuji Nishimura,Dai Matsuse,Hiroaki Sekiya,Katsuhisa Masaki,Tatsunori Tanaka,Toru Saiga,Masaya Harada, Yuu-ichi Kira,Dennis W. Dickson,Kei Fujishima,Eriko Matsuo,Kenji F. Tanaka,Ryo Yamasaki,Noriko Isobe,Jun-ichi Kira

Brain Behavior and Immunity（2024）

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关键词

Multiple system atrophy,alpha-synuclein,alpha-synuclein oligomer,Phosphorylated alpha-synuclein aggregate,Demyelination,Microglia,Transgenic mouse model,Tet-Off system

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