Pinnick Oxidation on Scale: Process Development of a BDK Inhibitor

Joel T. Arcari, Catherine Buckley,Leanne M. Buzon, Yongbo Dan, Timothy Houck, Zuxi Jin, Chao Li, Peifang Li, Kai Liu,Yiyang Liu,Javier Magano,Luis A. Martinez-Alsina, Bao Nguyen, Robert Pearson,Jared L. Piper,John A. Ragan,Matthew R. Reese, Wanli Tian, Jared Van Haitsma,Michael G. Vetelino, Yuan Zhang

Organic Process Research & Development（2024）

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Key words

BDK inhibitor,Pinnick oxidation,process safety,oxidation on larger scale

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