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Xibining Inhibition of the Pi3k-Akt Pathway Reduces M1 Macrophage Polarization to Ameliorate Koa Synovial Inflammation and Nociceptive Sensitization

Lishi Jie,Li Zhang, Houyu Fu,Junfeng Kang,Zeling Huang,Zaishi Zhu,Songjiang Yin,Peng Wu,Peimin Wang,Wei Mei,Xiaochen Li

PHYTOMEDICINE（2025）

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Key words
PI3K-AKT pathway,Intrinsic immunity,Macrophage polarization,Dorsal root ganglion,Knee osteoarthritis,TRP ion channels
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