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The Lethal K18-hACE2 Knock-in Mouse Model Mimicking the Severe Pneumonia of COVID-19 is Practicable for Antiviral Development

Zhen Zhang,Li Zhou,Qianyun Liu,Yucheng Zheng,Xue Tan,Zhixiang Huang,Ming Guo,Xin Wang,Xianying Chen,Simeng Liang,Wenkang Li,Kun Song,Kun Yan,Jiali Li,Qiaohong Li,Yuzhen Zhang,Shimin Yang,Zeng Cai,Ming Dai,Qiaoyang Xian,Zheng-Li Shi,Ke Xu,Ke Lan,Yu Chen

EMERGING MICROBES & INFECTIONS（2024）

Cited 6|Views38
Key words
SARS-CoV-2,mouse model,K18-hACE2 knock-in mouse,severe pneumonia,Omicron,antivirals
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