Analytical Validation and Clinical Utilization of K-4CARE™: a Comprehensive Genomic Profiling Assay with Personalized MRD Detection

Thien-Phuc Nguyen Hoang,Tien Anh Nguyen,Nam H. B. Tran,Van-Anh Nguyen Hoang,Hong Thuy Thi Dao,Vu-Uyen Tran,Yen Nhi Nguyen,Anh Tuan Nguyen,Cam Tu Nguyen Thi,Thanh Thuy Do Thi,Duy Sinh Nguyen,Hoai-Nghia Nguyen,Hoa Giang,Lan N. Tu

Frontiers in Molecular Biosciences（2024）

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Key words

comprehensive genomic profiling,tumor mutational burden,microsatellite instability,minimal residual disease,ctdna (circulating tumor DNA),targeted therapy,immunotherapy,immune checkpoint inhibitor (ICI)

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