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Fragment-Based NMR Screening of the BPTF PHD Finger Methyl Lysine Reader Leads to the First Small-Molecule Inhibitors.

Caroline R. Buchholz, Molly S. Sneddon, Joseph E. Mcpherson,Sourav Das,Clifford T. Gee,Michael J. Grillo,Sergio C. Chai,Richard E. Lee,Taosheng Chen,Daniel A. Harki,Anang A. Shelat,William C. K. Pomerantz

ACS Medicinal Chemistry Letters（2023）

引用 2|浏览22
关键词
BPTF,PHD finger,Methyl lysine reader,Fragment-based screening,Epigenetics
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