Multimodal Profiling of Peripheral Blood Identifies Proliferating Circulating Effector CD4+ T Cells As Predictors for Response to Integrin Α4β7-Blocking Therapy in Patients with Inflammatory Bowel Disease

Veronika Horn, Camila A. Cancino,Lisa M. Steinheuer,Benedikt Obermayer,Konstantin Fritz, Anke L. Nguyen, Kim Susan Juhran,Christina Plattner, Diana Boesel, Lotte Oldenburg, Marie Burns,Axel Ronald Schulz, Mariia Saliutina, Eleni Mantzivi,Donata Lissner, Thomas Conrad, Mir-Farzin Mashreghi, Sebastian Zundler,Elena Sonnenberg,Michael Schumann,Lea-Maxie Haag,Dieter Beule, Lukas Flatz, T. R. R. IBDome TRR IBDome Consortium,Zlatko Trajanoski,Geert D'Haens,Carl Weidinger,Henrik E. Mei,Britta Siegmund,Kevin Thurley,Ahmed N. Hegazy

GASTROENTEROLOGY（2025）

Cited 2|Views38

Key words

Inflammatory Bowel Disease,Cell Migration and Homing,Integrin a 4 6 7,CD4+Memory T Cells,Vedoli- zumab,Single-Cell Profiling,Machine Learning,Therapy Response

AI Read Science

Must-Reading Tree

Example

Generate MRT to find the research sequence of this paper

Chat Paper

Summary is being generated by the instructions you defined