the Discovery and Characterization of CFT1946: A Potent, Selective, and Orally Bioavailable Degrader of Mutant BRAF for the Treatment of BRAF-driven Cancers Yanke Liang , Mathew E. Sowa , Katrina L. Jackson , Jeffrey R. Simard , Bridget Kreger , Ping Li , Laura Poling , Joelle Baddour , Andrew Good , Hongwei Huang , Scott Eron , Christopher G. Nasveschuk , Robert Yu , Mark Fitzgerald , Victoria Garza , Morgan W. O'Shea , Gesine Veits , Jeremy Y. Yap , Moses Moustakim , Ashley Hart , Roman V. Agafonov , Grace Sarkissian , Joe S. Patel , Richard Deibler , Kyle S. Cole , David Cocozziello , Fazlur Rahman , Andrew J. Phillips , Elizabeth Norton , Adam S. Crystal , Roy M. Pollock , Stewart L. Fisher CANCER RESEARCH(2023)
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BRAF gene, Protein Degradation
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