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Spectrum and Frequency of Germline FANCM Protein-Truncating Variants in 44,803 European Female Breast Cancer Cases

Gisella Figlioli,Amandine Billaud,Qin Wang,Manjeet K. Bolla,Joe Dennis,Michael Lush,Anders Kvist,Muriel A. Adank,Thomas U. Ahearn,Natalia N. Antonenkova,Paeivi Auvinen,Sabine Behrens,Marina Bermisheva,Natalia Bogdanova,Stig E. Bojesen,Bernardo Bonanni,Thomas Bruening,Nicola J. Camp,Archie Campbell,Jose E. Castelao,Melissa H. Cessna,Kamila Czene,Peter Devilee,Thilo Doerk,Mikael Eriksson,Peter A. Fasching,Henrik Flyger,Marike Gabrielson,Manuela Gago-Dominguez,Montserrat Garcia-Closas,Gord Glendon,Encarna Gomez Garcia,Anna Gonzalez-Neira,Felix Grassmann,Pascal Guenel,Eric Hahnen,Ute Hamann,Peter Hillemanns,Maartje J. Hooning,Reiner Hoppe,Anthony Howell,Keith Humphreys,Anna Jakubowska,Elza K. Khusnutdinova,Vessela N. Kristensen,Annika Lindblom,Maria A. Loizidou,Jan Lubinski,Arto Mannermaa,Tabea Maurer,Dimitrios Mavroudis,William G. Newman,Nadia Obi,Mihalis Panayiotidis,Paolo Radice,Muhammad U. Rashid,Valerie Rhenius,Matthias Ruebner,Emmanouil Saloustros,Elinor J. Sawyer,Marjanka K. Schmidt,Rita K. Schmutzler,Mitul T. Shah,Melissa C. Southey,Ian Tomlinson,Therese Truong,Elke M. van Veen,Camilla Wendt,Xiaohong R. Yang,Kyriaki Michailidou,Alison M. Dunning,Paul D. P. Pharoah,Douglas F. Easton,Irene L. Andrulis,D. Gareth Evans,Antoinette Hollestelle,Jenny Chang-Claude,Roger L. Milne,Paolo Peterlongo

CANCERS（2023）

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关键词
breast cancer predisposition,breast cancer risk factors,FANCM PTVs spectrum,protein truncating variants,PTVs
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