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Irisin Acts Through Its Integrin Receptor in a Two-Step Process Involving Extracellular Hsp90α

A. Mu,Thomas E. Wales,Haixia Zhou,Sorin-Valeriu Draga-Coleta,Christoph Gorgulla,Katherine A. Blackmore,Melanie J. Mittenbuhler,Caroline R. Kim,Dina Bogoslavski, Qiuyang Zhang,Zi-Fu Wang,Mark P. Jedrychowski,Hyuk-Soo Seo,Kijun Song,Andrew Z. Xu,Luke Sebastian,Steven P. Gygi,Haribabu Arthanari,Sirano Dhe-Paganon,Patrick R. Griffin,John R. Engen,Bruce M. Spiegelman

MOLECULAR CELL（2023）

Cited 16|Views2
Key words
irisin,exercise,integrin,extracellular Hsp90,integrin activation,fibronectin III domain,ligand binding,RGD motif,HDX-MS,protein-protein docking
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