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Evidence for Broad Cross-Reactivity of the SARS-CoV-2 NSP12-directed CD4+ T-cell Response with Pre-Primed Responses Directed Against Common Cold Coronaviruses.

Tim Westphal,Maria Mader,Hendrik Karsten,Leon Cords,Maximilian Knapp,Sophia Schulte,Lennart Hermanussen,Sven Peine,Vanessa Ditt,Alba Grifoni,Marylyn Martina Addo,Samuel Huber,Alessandro Sette,Marc Luetgehetmann,Sven Pischke,William W. W. Kwok,John Sidney,Julian Schulze zur Wiesch

FRONTIERS IN IMMUNOLOGY（2023）

Cited 5|Views76
Key words
SARS-CoV-2,NSP12,CD4+T-cells,RNA-dependant RNA polymerase,Cross-reactivities,epitope analysis,sequence identities,common cold coronaviruses
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