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The P323L Substitution in the SARS-CoV-2 Polymerase (NSP12) Confers a Selective Advantage During Infection

Hannah Goldswain,Xiaofeng Dong,Rebekah Penrice-Randal,Muhannad Alruwaili,Ghada T. Shawli,Tessa Prince,Maia Kavanagh Williamson,Jayna Raghwani,Nadine Randle,Benjamin Jones,I’ah Donovan-Banfield,Francisco J. Salguero,Julia A. Tree,Yper Hall,Catherine Hartley,Maximilian Erdmann,James Bazire,Tuksin Jearanaiwitayakul,Malcolm G. Semple,Peter J. M. Openshaw,J. Kenneth Baillie,Stevan R. Emmett,Paul Digard,David A. Matthews,Lance Turtle,Alistair C. Darby,Andrew D. Davidson,Miles W. Carroll,Julian A. Hiscox

Genome Biology（2023）

Cited 16|Views43
Key words
SARS-CoV-2,Evolution,Selection,Spike protein,Polymerase,NSP12,COVID-19,P323L
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