LEUKOCYTE PHENOTYPING IN SEPSIS USING OMICS, FUNCTIONAL ANALYSIS, AND IN SILICO MODELING.
SHOCK（2023）
Key words
Sepsis,heterogeneous,omics,immunophenotyping,immune cells,organ-on-chip,BPs -- Biological processes,DEGs -- Differentially expressed genes,DEPs -- Differentially expressed proteins,EC,ECs -- Endothelial cell(s),GO -- Gene ontology,KEGG -- Kyoto Encyclopedia of Genes and Genomes,LDNs -- Low-density neutrophils,ML -- Machine learning,MODS -- Multiple organ dysfunction syndrome,MPO -- Myeloperoxidase,MPS -- Microphysiological system,NETs -- Neutrophil extracellular traps,PAMPs -- Pathogen-associated molecular patterns,PPI -- Protein-protein interaction,PRRs -- Pathogen recognition receptors,RNSs -- Reactive nitrogen species,ROS -- Reactive oxygen species,STRING -- Search tool for the retrieval of interacting genes,proteins,WGCNA -- Weighted gene correlation network analysis
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