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Biochemical and Structural Basis for Differential Inhibitor Sensitivity of EGFR with Distinct Exon 19 Mutations.

Iris K. van Alderwerelt van Rosenburgh, David M. Lu,Michael J. Grant,Steven E. Stayrook,Manali Phadke,Zenta Walther,Sarah B. Goldberg,Katerina Politi,Mark A. Lemmon,Kumar D. Ashtekar,Yuko Tsutsui

Nature communications（2022）

Cited 10|Views36
Key words
Cancer therapeutic resistance,Kinases,Non-small-cell lung cancer,X-ray crystallography,Science,Humanities and Social Sciences,multidisciplinary
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