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Atroposelective Negishi Coupling Optimization Guided by Multivariate Linear Regression Analysis: Asymmetric Synthesis of KRAS G12C Covalent Inhibitor GDC-6036

Jie Xu,Samantha Grosslight,Kyle A. Mack,Sierra C. Nguyen,Kyle Clagg,Ngiap-Kie Lim,Jacob C. Timmerman,Jeff Shen,Nicholas A. White,Lauren E. Sirois,Chong Han,Haiming Zhang,Matthew S. Sigman,Francis Gosselin

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY（2022）

Cited 25|Views19
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