全凭静脉麻醉和静吸复合麻醉对老年肺癌根治术患者麻醉质量及术后认知功能的影响
Journal of North Sichuan Medical College（2022）
Abstract
目的:探讨全凭静脉麻醉和静吸复合麻醉对老年肺癌根治术患者麻醉质量、应激反应指标及术后认知功能的影响.方法:选取110例肺癌根治术的老年患者为研究对象,按照麻醉方式不同分为观察组(n=58)和对照组(n=52).观察组患者行全凭静脉麻醉;对照组患者行静吸复合麻醉.比较两组患者围术期指标、麻醉质量、应激反应、血流动力学和认知功能.结果:观察组患者插管时间、麻醉时间、麻醉起效时间、睁眼时间、定向力恢复时间、听从指令时间低于对照组(P<0.05).T1、T2、T3时,观察组肾上腺素(E)、心率(HR)水平低于对照组(P<0.05).麻醉后12 h、24 h,观察组MMSE评分高于对照组(P<0.05).结论:全凭静脉麻醉和静吸复合麻醉应用于老年肺癌根治术均有良好效果,但全凭静脉麻醉麻醉质量更好,对患者应激反应、术后短期认知功能的影响较小.
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