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Complement Activation Induces Excessive T Cell Cytotoxicity in Severe COVID-19

Philipp Georg,Rosario Astaburuaga-Garcia,Lorenzo Bonaguro,Sophia Brumhard,Laura Michalick,Lena J. Lippert,Tomislav Kostevc,Christiane Gaebel,Maria Schneider,Mathias Streitz,Vadim Demichev,Ioanna Gemuend,Matthias Barone,Pinkus Tober-Lau,Elisa T. Helbig,David Hillus,Lev Petrov,Julia Stein,Hannah-Philine Dey,Daniela Paclik,Christina Iwert,Michael Muelleder,Simran Kaur Aulakh,Sonja Djudjaj,Roman D. Buelow,Henrik E. Mei,Axel R. Schulz,Andreas Thiel,Stefan Hippenstiel,Antoine-Emmanuel Saliba,Roland Eils,Irina Lehmann,Marcus A. Mall,Sebastian Stricker,Jobst Roehmel,Victor M. Corman,Dieter Beule,Emanuel Wyler,Markus Landthaler,Benedikt Obermayer,Saskia von Stillfried,Peter Boor,Munevver Demir,Hans Wesselmann,Norbert Suttorp,Alexander Uhrig,Holger Mueller-Redetzky,Jacob Nattermann,Wolfgang M. Kuebler,Christian Meisel,Markus Ralser,Joachim L. Schultze,Anna C. Aschenbrenner,Charlotte Thibeault,Florian Kurth,Leif E. Sander,Nils Bluethgen,Birgit Sawitzki

Cell（2021）

Cited 141|Views32
Key words
COVID-19,T cells,complement,cytotoxicity,immunopathology
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