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Profiling SARS-CoV-2 HLA-I Peptidome Reveals T Cell Epitopes from Out-of-frame ORFs

Shira Weingarten-Gabbay,Susan Klaeger,Siranush Sarkizova,Leah R. Pearlman,Da-Yuan Chen,Kathleen M. E. Gallagher,Matthew R. Bauer,Hannah B. Taylor,W. Augustine Dunn,Christina Tarr,John Sidney,Suzanna Rachimi,Hasahn L. Conway,Katelin Katsis,Yuntong Wang,Del Leistritz-Edwards, Melissa R. Durkin,Christopher H. Tomkins-Tinch,Yaara Finkel,Aharon Nachshon,Matteo Gentili,Keith D. Rivera,Isabel P. Carulli,Vipheaviny A. Chea,Abishek Chandrashekar,Cansu Cimen Bozkus,Mary Carrington,Nina Bhardwaj,Dan H. Barouch,Alessandro Sette,Marcela Maus,Charles M. Rice,Karl R. Clauser,Derin B. Keskin,Daniel C. Pregibon,Nir Hacohen,Steven A. Carr,Jennifer G. Abelin,Mohsan Saeed,Pardis C. Sabeti

Cell（2021）

Cited 110|Views58
Key words
SARS-CoV-2,out-of-frame ORF immunopeptidomics,T Cell response,immunogenicity,HLA Class I,viral infection,coronavirus
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