Modulating Target Protein Biology Through the Re-mapping of Conformational Distributions Using Small Molecules

Alastair D. G. Lawson,Malcolm MacCoss, Dominique L. Baeten,Alex Macpherson,Jiye Shi,Alistair J. Henry

Frontiers in Chemistry（2021）

Cited 3|Views19

Key words

protein-protein interactions,conformational sampling,conformational distributions,conformer,allosteric,small molecule,drug discovery,molecular dynamics

AI Read Science

Must-Reading Tree

Example

Generate MRT to find the research sequence of this paper

Chat Paper

Summary is being generated by the instructions you defined