Activation of HERV-K(HML-2) Disrupts Cortical Patterning and Neuronal Differentiation by Increasing NTRK3

Vidya Padmanabhan Nair,Hengyuan Liu,Gabriele Ciceri,Johannes Jungverdorben,Goar Frishman,Jason Tchieu,Gustav Y. Cederquist,Ina Rothenaigner,Kenji Schorpp,Lena Klepper,Ryan M. Walsh,Tae Wan Kim,Daniela Cornacchia,Andreas Ruepp,Jens Mayer,Kamyar Hadian,Dmitrij Frishman,Lorenz Studer,Michelle Vincendeau

Cell stem cell（2021）

Cited 32|Views40

Key words

HERV,endogenous retrovirus,retrotransposon,CRISPR,influencing cortical neuronal development,Neurotrophic Tyrosine Receptor Kinase 3,NTRK3,forebrain orgnoid

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