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Structure-Based Approaches to Improving Selectivity Through Utilizing Explicit Water Molecules: Discovery of Selective Β-Secretase (BACE1) Inhibitors over BACE2

Kazuki Fujimoto,Shuhei Yoshida,Genta Tadano,Naoya Asada,Kouki Fuchino,Shinji Suzuki,Eriko Matsuoka,Takahiko Yamamoto,Shiho Yamamoto,Shigeru Ando,Naoki Kanegawa,Yutaka Tonomura,Hisanori Ito,Diederik Moechars,Frederik J. R. Rombouts,Harrie J. M. Gijsen,Ken-ichi Kusakabe

Journal of Medicinal Chemistry（2021）

引用 14|浏览24
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