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    • 持续性血液净化用于糖尿病肾病急性肾衰竭伴酮症酸中毒患者治疗中的临床分析

    冯俊,谢辉,黄秋杰, 官智敏

    Diabetes New World（2019）

    Cited 2|Views18
    Abstract
    目的 分析持续性血液净化(CBP)用于糖尿病肾病(DN)急性肾衰竭(ARF)伴酮症酸中毒患者治疗中的临床疗效.方法 选取2016年1月—2018年12月该院收治的58例行CBP治疗的DN合并ARF伴酮症酸中毒患者,随机分为对照组、研究组,各29例.研究组采用CBP治疗,对照组采用常规间歇性血液净化治疗.治疗1个月,比较两组治疗效果.结果 研究组存活率为96.55%、死亡率为3.45%与对照组(89.66%、10.34%)比较差异无统计学意义(P＞0.05);研究组二氧化碳结合力(CO2CP)(18.6±9.6)mmol/L、渗透压(OP)(321.4±17.8)mmHg、水平明显高于对照组(14.6± 8.8)mmol/L、(268.5±15.9)mmHg,且研究组空腹血糖(GLU)(12.7±1.9)mmol/L、肌酐(Cr)(156.3±68.4)mmol/L、尿素氮(BUN)(12.4±5.1)mmol/L均低于对照组(17.2±2.4)mmol/L、(248.4±74.5)mmol/L、(20.6±6.4)mmol/L,差异有统计学意义(P＜0.05).结论 CBP技术能改善机体缺氧症状,提高氧合功能,改善机体水电解质紊乱、糖代谢紊乱、酸碱失衡症状,降低患者死亡率,对DN合并ARF伴酮症酸中毒患者疗效显著,值得推广.
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    【要点】：该论文研究了持续性血液净化(CBP)在糖尿病肾病(DN)合并急性肾衰竭(ARF)伴酮症酸中毒患者中的应用，证明了其能显著改善患者症状并降低死亡率。
    

    【方法】：通过对比实验，将患者随机分为采用CBP治疗的研究组和采用常规间歇性血液净化治疗的对照组，治疗一个月后比较两组治疗效果。
    

    【实验】：选取2016年1月至2018年12月该院收治的58例行CBP治疗的DN合并ARF伴酮症酸中毒患者，数据集未明确提及，结果显示研究组在二氧化碳结合力、渗透压、空腹血糖、肌酐和尿素氮等指标上均优于对照组，表明CBP治疗具有显著疗效。